WAY-213613 hydrochloride

CAS No. 2450268-84-3

WAY-213613 hydrochloride( —— )

Catalog No. M26506 CAS No. 2450268-84-3

WAY-213613 hydrochloride is a selective nonsubstrate reuptake GLT-1/EAAT2 inhibitor (IC50: 85 nM, EAAT2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 115 Get Quote
10MG 155 Get Quote
25MG 357 Get Quote
50MG 597 Get Quote
100MG 1017 Get Quote
200MG 1377 Get Quote
500MG 2061 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    WAY-213613 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    WAY-213613 hydrochloride is a selective nonsubstrate reuptake GLT-1/EAAT2 inhibitor (IC50: 85 nM, EAAT2).
  • Description
    WAY-213613 hydrochloride is a selective nonsubstrate reuptake GLT-1/EAAT2 inhibitor (IC50: 85 nM, EAAT2). WAY-213613 hydrochloride displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Cleavable
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2450268-84-3
  • Formula Weight
    451.65
  • Molecular Formula
    C16H14BrClF2N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (110.71 mMw)
  • SMILES
    BrC(C=C(F)C(F)=C1)=C1OC2=CC=C(NC(C[C@H](N)C(O)=O)=O)C=C2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.
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